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Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity
Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis Group
2019-01-01
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| 叢編: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| 主題: | |
| 在線閱讀: | http://dx.doi.org/10.1080/14756366.2018.1538980 |
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