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Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity

Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...

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Dades bibliogràfiques
Publicat a:J Enzyme Inhib Med Chem
Autors principals: Logozzi, Mariantonia, Capasso, Clemente, Di Raimo, Rossella, Del Prete, Sonia, Mizzoni, Davide, Falchi, Mario, Supuran, Claudiu T., Fais, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327996/
https://ncbi.nlm.nih.gov/pubmed/30734594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1538980
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