Germline TP53 and MSH6 mutations implicated in sporadic triple-negative breast cancer (TNBC): a preliminary study

BACKGROUND: Germline BRCA1/2 prevalence is relatively low in sporadic triple-negative breast cancer (TNBC). We hypothesized that non-BRCA genes may also have significant germline contribution to Chinese sporadic TNBC, and the somatic mutational landscape of TNBC may vary between ethnic groups. We th...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Yi, Dandan, Xu, Lei, Luo, Jiaqi, You, Xiaobin, Huang, Tao, Zi, Yi, Li, Xiaoting, Wang, Ru, Zhong, Zaixuan, Tang, Xiaoqiao, Li, Ang, Shi, Yujian, Rao, Jianmei, Zhang, Yifen, Sang, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327518/
https://ncbi.nlm.nih.gov/pubmed/30630526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0186-y
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