Prevalence of Pathological Germline Mutations of hMLH1 and hMSH2 Genes in Colorectal Cancer

The prevalence of pathological germline mutations in colorectal cancer has been widely studied, as germline mutations in the DNA mismatch repair genes hMLH1 and hMSH2 confer a high risk of colorectal cancer. However, because the sample size and population of previous studies are very different from...

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Detalhes bibliográficos
Main Authors: Li, Dandan, Hu, Fulan, Wang, Fan, Cui, Binbin, Dong, Xinshu, Zhang, Wencui, Lin, Chunqing, Li, Xia, Wang, Da, Zhao, Yashuang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602519/
https://ncbi.nlm.nih.gov/pubmed/23526924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051240
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