Novel DNA Variants and Mutation Frequencies of hMLH1 and hMSH2 Genes in Colorectal Cancer in the Northeast China Population

Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal cancer (CRC). No studies to date have assessed the role of hMLH1 and hMSH2 genes in mass sporadic CRC (without preselection by MSI or early age of onset). We aimed to identify novel hMLH1 and hMSH2 DNA...

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Hlavní autoři: Hu, Fulan, Li, Dandan, Wang, Yibaina, Yao, Xiaoping, Zhang, Wencui, Liang, Jing, Lin, Chunqing, Ren, Jiaojiao, Zhu, Lin, Wu, Zhiwei, Li, Shuying, Li, Ye, Zhao, Xiaojuan, Cui, Binbin, Dong, Xinshu, Tian, Suli, Zhao, Yashuang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616036/
https://ncbi.nlm.nih.gov/pubmed/23573243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060233
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