Germline TP53 Variants and Susceptibility to Osteosarcoma

The etiologic contribution of germline genetic variation to sporadic osteosarcoma is not well understood. Osteosarcoma is a sentinel cancer of Li-Fraumeni syndrome (LFS), in which approximately 70% of families meeting the classic criteria have germline TP53 mutations. We sequenced TP53 exons in 765...

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Bibliografische gegevens
Gepubliceerd in:J Natl Cancer Inst
Hoofdauteurs: Mirabello, Lisa, Yeager, Meredith, Mai, Phuong L., Gastier-Foster, Julie M., Gorlick, Richard, Khanna, Chand, Patiño-Garcia, Ana, Sierrasesúmaga, Luis, Lecanda, Fernando, Andrulis, Irene L., Wunder, Jay S., Gokgoz, Nalan, Barkauskas, Donald A., Zhang, Xijun, Vogt, Aurelie, Jones, Kristine, Boland, Joseph F., Chanock, Stephen J., Savage, Sharon A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Brief Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651039/
https://ncbi.nlm.nih.gov/pubmed/25896519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv101
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