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Germline TP53 Variants and Susceptibility to Osteosarcoma
The etiologic contribution of germline genetic variation to sporadic osteosarcoma is not well understood. Osteosarcoma is a sentinel cancer of Li-Fraumeni syndrome (LFS), in which approximately 70% of families meeting the classic criteria have germline TP53 mutations. We sequenced TP53 exons in 765...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Natl Cancer Inst |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651039/ https://ncbi.nlm.nih.gov/pubmed/25896519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv101 |
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