The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation

OBJECTIVE: Organic nitrates such as isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) are used for the treatment of patients with chronic symptomatic stable coronary artery disease and chronic congestive heart failure. Limiting side effects of these nitrovasodilators include nitrate to...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Steven, Sebastian, Oelze, Matthias, Hausding, Michael, Roohani, Siyer, Kashani, Fatemeh, Kröller-Schön, Swenja, Helmstädter, Johanna, Jansen, Thomas, Baum, Christine, Iglarz, Marc, Schulz, Eberhard, Münzel, Thomas, Daiber, Andreas
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327264/
https://ncbi.nlm.nih.gov/pubmed/30687454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7845629
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