The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation

OBJECTIVE: Organic nitrates such as isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) are used for the treatment of patients with chronic symptomatic stable coronary artery disease and chronic congestive heart failure. Limiting side effects of these nitrovasodilators include nitrate to...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Steven, Sebastian, Oelze, Matthias, Hausding, Michael, Roohani, Siyer, Kashani, Fatemeh, Kröller-Schön, Swenja, Helmstädter, Johanna, Jansen, Thomas, Baum, Christine, Iglarz, Marc, Schulz, Eberhard, Münzel, Thomas, Daiber, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327264/
https://ncbi.nlm.nih.gov/pubmed/30687454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7845629
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