The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation

OBJECTIVE: Organic nitrates such as isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) are used for the treatment of patients with chronic symptomatic stable coronary artery disease and chronic congestive heart failure. Limiting side effects of these nitrovasodilators include nitrate to...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Steven, Sebastian, Oelze, Matthias, Hausding, Michael, Roohani, Siyer, Kashani, Fatemeh, Kröller-Schön, Swenja, Helmstädter, Johanna, Jansen, Thomas, Baum, Christine, Iglarz, Marc, Schulz, Eberhard, Münzel, Thomas, Daiber, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327264/
https://ncbi.nlm.nih.gov/pubmed/30687454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7845629
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