Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency

The genome of pluripotent stem cells adopts a unique three-dimensional architecture featuring weakly condensed heterochromatin and large nucleosome-free regions. Yet, it is unknown whether structural loops and contact domains display characteristics that distinguish embryonic stem cells (ESCs) from...

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Publicat a:Cell Syst
Autors principals: Pękowska, Aleksandra, Klaus, Bernd, Xiang, Wanqing, Severino, Jacqueline, Daigle, Nathalie, Klein, Felix A., Oleś, Małgorzata, Casellas, Rafael, Ellenberg, Jan, Steinmetz, Lars M., Bertone, Paul, Huber, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327227/
https://ncbi.nlm.nih.gov/pubmed/30414923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.09.003
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