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Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis

Successful metastasis requires the co-evolution of stromal and cancer cells. We used stable isotope labeling of amino acids in cell culture (SILAC) coupled with quantitative, label-free phosphoproteomics to study the bidirectional signaling in ovarian cancer cells and human-derived, cancer-associate...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Curtis, Marion, Kenny, Hilary A., Ashcroft, Bradley, Mukherjee, Abir, Johnson, Alyssa, Zhang, Yilin, Helou, Ynes, Batlle, Raquel, Liu, Xiaojing, Gutierrez, Nuria, Gao, Xia, Yamada, S. Diane, Lastra, Ricardo, Montag, Anthony, Ahsan, Nagib, Locasale, Jason W., Salomon, Arthur R., Nebreda, Angel R., Lengyel, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326875/
https://ncbi.nlm.nih.gov/pubmed/30174305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.08.007
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