Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis

Successful metastasis requires the co-evolution of stromal and cancer cells. We used stable isotope labeling of amino acids in cell culture (SILAC) coupled with quantitative, label-free phosphoproteomics to study the bidirectional signaling in ovarian cancer cells and human-derived, cancer-associate...

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I publikationen:Cell Metab
Huvudupphovsmän: Curtis, Marion, Kenny, Hilary A., Ashcroft, Bradley, Mukherjee, Abir, Johnson, Alyssa, Zhang, Yilin, Helou, Ynes, Batlle, Raquel, Liu, Xiaojing, Gutierrez, Nuria, Gao, Xia, Yamada, S. Diane, Lastra, Ricardo, Montag, Anthony, Ahsan, Nagib, Locasale, Jason W., Salomon, Arthur R., Nebreda, Angel R., Lengyel, Ernst
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326875/
https://ncbi.nlm.nih.gov/pubmed/30174305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.08.007
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