Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication

Hepatitis C virus (HCV) infection is a major cause of human chronic liver disease and hepatocellular carcinoma. G-quadruplex (G4) is an important four-stranded secondary structure of nucleic acids. Recently, we discovered that the core gene of HCV contains a G4 RNA structure; however, the interactio...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Bian, Wen-Xiu, Xie, Yan, Wang, Xiao-Ning, Xu, Guo-Hua, Fu, Bo-Shi, Li, Shu, Long, Gang, Zhou, Xiang, Zhang, Xiao-Lian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Chemical Biology and Nucleic Acid Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326805/
https://ncbi.nlm.nih.gov/pubmed/30462330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1177
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