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DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex

Cortical development is controlled by transcriptional programs, which are orchestrated by transcription factors. Yet, stable inheritance of spatio-temporal activity of factors influencing cell fate and localization in different layers is only partly understood. Here we find that deletion of Dot1l in...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Franz, Henriette, Villarreal, Alejandro, Heidrich, Stefanie, Videm, Pavankumar, Kilpert, Fabian, Mestres, Ivan, Calegari, Federico, Backofen, Rolf, Manke, Thomas, Vogel, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326801/
https://ncbi.nlm.nih.gov/pubmed/30329130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky953
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