Single-molecule imaging of DNA gyrase activity in living Escherichia coli

Bacterial DNA gyrase introduces negative supercoils into chromosomal DNA and relaxes positive supercoils introduced by replication and transiently by transcription. Removal of these positive supercoils is essential for replication fork progression and for the overall unlinking of the two duplex DNA...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Stracy, Mathew, Wollman, Adam J M, Kaja, Elzbieta, Gapinski, Jacek, Lee, Ji-Eun, Leek, Victoria A, McKie, Shannon J, Mitchenall, Lesley A, Maxwell, Anthony, Sherratt, David J, Leake, Mark C, Zawadzki, Pawel
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326794/
https://ncbi.nlm.nih.gov/pubmed/30445553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1143
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