Single-molecule imaging of DNA gyrase activity in living Escherichia coli

Bacterial DNA gyrase introduces negative supercoils into chromosomal DNA and relaxes positive supercoils introduced by replication and transiently by transcription. Removal of these positive supercoils is essential for replication fork progression and for the overall unlinking of the two duplex DNA...

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Udgivet i:Nucleic Acids Res
Main Authors: Stracy, Mathew, Wollman, Adam J M, Kaja, Elzbieta, Gapinski, Jacek, Lee, Ji-Eun, Leek, Victoria A, McKie, Shannon J, Mitchenall, Lesley A, Maxwell, Anthony, Sherratt, David J, Leake, Mark C, Zawadzki, Pawel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326794/
https://ncbi.nlm.nih.gov/pubmed/30445553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1143
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