Vibrio cholerae ParE2 Poisons DNA Gyrase via a Mechanism Distinct from Other Gyrase Inhibitors

DNA gyrase is an essential bacterial enzyme required for the maintenance of chromosomal DNA topology. This enzyme is the target of several protein toxins encoded in toxin-antitoxin (TA) loci as well as of man-made antibiotics such as quinolones. The genome of Vibrio cholerae, the cause of cholera, c...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuan, Jie, Sterckx, Yann, Mitchenall, Lesley A., Maxwell, Anthony, Loris, Remy, Waldor, Matthew K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001019/
https://ncbi.nlm.nih.gov/pubmed/20952390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138776
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items