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Comparison between continuous and discrete doses for model based designs in cancer dose finding
Despite of an extensive statistical literature showing that discretizing continuous variables results in substantial loss of information, categorization of continuous variables has been a common practice in clinical research and in cancer dose finding (phase I) clinical trials. The objective of this...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326565/ https://ncbi.nlm.nih.gov/pubmed/30625194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210139 |
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