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Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes

Repression of retrotransposons is essential for genome integrity during germ cell development and is tightly controlled through epigenetic mechanisms. In primordial germ cells, protein arginine N‐methyltransferase (Prmt5) is involved in retrotransposon repression by methylating Piwi proteins, which...

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Bibliografske podrobnosti
izdano v:FEBS Open Bio
Main Authors: Paul, Conception, Delpech, Hélène, Haouzi, Delphine, Hamamah, Samir, Sardet, Claude, Fabbrizio, Eric
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325579/
https://ncbi.nlm.nih.gov/pubmed/30652083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12562
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