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Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes

Repression of retrotransposons is essential for genome integrity during germ cell development and is tightly controlled through epigenetic mechanisms. In primordial germ cells, protein arginine N‐methyltransferase (Prmt5) is involved in retrotransposon repression by methylating Piwi proteins, which...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Paul, Conception, Delpech, Hélène, Haouzi, Delphine, Hamamah, Samir, Sardet, Claude, Fabbrizio, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325579/
https://ncbi.nlm.nih.gov/pubmed/30652083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12562
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