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Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes
Repression of retrotransposons is essential for genome integrity during germ cell development and is tightly controlled through epigenetic mechanisms. In primordial germ cells, protein arginine N‐methyltransferase (Prmt5) is involved in retrotransposon repression by methylating Piwi proteins, which...
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| Udgivet i: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325579/ https://ncbi.nlm.nih.gov/pubmed/30652083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12562 |
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