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Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein

BACKGROUND AND PURPOSE: Disruption of nucleoporins has been reported in the motor neurons of patients with sporadic amyotrophic lateral sclerosis (sALS). However, the precise changes in the morphology of nucleoporins associated with the pathology of the 43-kDa TAR DNA-binding protein (TDP-43) in the...

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Detaylı Bibliyografya
Yayımlandı:J Clin Neurol
Asıl Yazarlar: Aizawa, Hitoshi, Yamashita, Takenari, Kato, Haruhisa, Kimura, Takashi, Kwak, Shin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Korean Neurological Association 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325357/
https://ncbi.nlm.nih.gov/pubmed/30618218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3988/jcn.2019.15.1.62
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