CD48 and α7 Nicotinic Acetylcholine Receptor Synergistically Regulate FimH-Mediated Escherichia coli K1 Penetration and Neutrophil Transmigration Across Human Brain Microvascular Endothelial Cells

FimH-mediated bacterial invasion and polymorphonuclear neutrophil (PMN) transmigration across human brain microvascular endothelial cells (HBMECs) are required for the pathogenesis of Escherichia coli meningitis. However, the underlying mechanism remains unclear. This study demonstrated that the Tnp...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Liu, Rui, Wu, Chao, Li, Li, Chi, Feng, Zhang, Tiesong, Xu, Yating, Ji, Lulu, Chen, Zhiguo, Hu, Hanyang, Zhang, Xiaoli, Huang, Shenghe, Wang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325351/
https://ncbi.nlm.nih.gov/pubmed/30202861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy531
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