CD48 and α7 Nicotinic Acetylcholine Receptor Synergistically Regulate FimH-Mediated Escherichia coli K1 Penetration and Neutrophil Transmigration Across Human Brain Microvascular Endothelial Cells

FimH-mediated bacterial invasion and polymorphonuclear neutrophil (PMN) transmigration across human brain microvascular endothelial cells (HBMECs) are required for the pathogenesis of Escherichia coli meningitis. However, the underlying mechanism remains unclear. This study demonstrated that the Tnp...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Liu, Rui, Wu, Chao, Li, Li, Chi, Feng, Zhang, Tiesong, Xu, Yating, Ji, Lulu, Chen, Zhiguo, Hu, Hanyang, Zhang, Xiaoli, Huang, Shenghe, Wang, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325351/
https://ncbi.nlm.nih.gov/pubmed/30202861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy531
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