Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides

Artesunate (AS), a semisynthetic artemisinin approved for malaria therapy, inhibits human cytomegalovirus (HCMV) replication in vitro, but therapeutic success in humans has been variable. We hypothesized that the short in vivo half-life of AS may contribute to the different treatment outcomes. We te...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wang, Yiping, Mukhopadhyay, Rupkatha, Roy, Sujayita, Kapoor, Arun, Su, Yu-Pin, Charman, Susan A., Chen, Gong, Wu, Jianbo, Wang, Xiaofang, Vennerstrom, Jonathan L., Arav-Boger, Ravit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325236/
https://ncbi.nlm.nih.gov/pubmed/30373792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01735-18
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