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Daptomycin Pore Formation and Stoichiometry Depend on Membrane Potential of Target Membrane
Daptomycin is a calcium-dependent lipodepsipeptide antibiotic clinically used to treat serious infections caused by Gram-positive pathogens. Its precise mode of action is somewhat controversial; the biggest issue is daptomycin pore formation, which we directly investigated here. We first performed a...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325215/ https://ncbi.nlm.nih.gov/pubmed/30323037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-18 |
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