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Promotion of homology-directed DNA repair by polyamines

Polyamines, often elevated in cancer cells, have been shown to promote cell growth and proliferation. Whether polyamines regulate other cell functions remains unclear. Here, we explore whether and how polyamines affect genome integrity. When DNA double-strand break (DSB) is induced in hair follicles...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Lee, Chih-Ying, Su, Guan-Chin, Huang, Wen-Yen, Ko, Min-Yu, Yeh, Hsin-Yi, Chang, Geen-Dong, Lin, Sung-Jan, Chi, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325121/
https://ncbi.nlm.nih.gov/pubmed/30622262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08011-1
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