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Promotion of homology-directed DNA repair by polyamines

Polyamines, often elevated in cancer cells, have been shown to promote cell growth and proliferation. Whether polyamines regulate other cell functions remains unclear. Here, we explore whether and how polyamines affect genome integrity. When DNA double-strand break (DSB) is induced in hair follicles...

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Publicat a:Nat Commun
Autors principals: Lee, Chih-Ying, Su, Guan-Chin, Huang, Wen-Yen, Ko, Min-Yu, Yeh, Hsin-Yi, Chang, Geen-Dong, Lin, Sung-Jan, Chi, Peter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325121/
https://ncbi.nlm.nih.gov/pubmed/30622262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08011-1
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