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Promotion of homology-directed DNA repair by polyamines

Polyamines, often elevated in cancer cells, have been shown to promote cell growth and proliferation. Whether polyamines regulate other cell functions remains unclear. Here, we explore whether and how polyamines affect genome integrity. When DNA double-strand break (DSB) is induced in hair follicles...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Chih-Ying, Su, Guan-Chin, Huang, Wen-Yen, Ko, Min-Yu, Yeh, Hsin-Yi, Chang, Geen-Dong, Lin, Sung-Jan, Chi, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325121/
https://ncbi.nlm.nih.gov/pubmed/30622262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08011-1
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