HACE1 is a potential tumor suppressor in osteosarcoma

Osteosarcoma is a malignant bone sarcoma characterized by extensive genomic disruption and a propensity for metastatic spread. Osteoid production suggests a close relationship with normal osteoblasts, and the latter are the presumptive cell of origin of this disease. The HACE1 gene, localized to hum...

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Publicat a:Cell Death Dis
Autors principals: El-Naggar, Amal M, Clarkson, Paul W., Negri, Gian Luca, Turgu, Busra, Zhang, Fan, Anglesio, Michael S., Sorensen, Poul H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325116/
https://ncbi.nlm.nih.gov/pubmed/30622235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1276-4
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