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Teaching an old dog new tricks: next-generation CAR T cells

Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for the treatment of CD19-positive leukaemias and lymphomas. CARs are synthetic rece...

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Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Tokarew, Nicholas, Ogonek, Justyna, Endres, Stefan, von Bergwelt-Baildon, Michael, Kobold, Sebastian
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325111/
https://ncbi.nlm.nih.gov/pubmed/30413825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0325-1
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