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Teaching an old dog new tricks: next-generation CAR T cells
Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for the treatment of CD19-positive leukaemias and lymphomas. CARs are synthetic rece...
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| Veröffentlicht in: | Br J Cancer |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325111/ https://ncbi.nlm.nih.gov/pubmed/30413825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0325-1 |
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