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Aurora kinase A drives the evolution of resistance to third generation EGFR inhibitors in lung cancer
Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between drug responsiveness, tolerance and resistance, especially in the absence of pre-existing subclones, remains u...
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| Vydáno v: | Nat Med |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324945/ https://ncbi.nlm.nih.gov/pubmed/30478424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0264-7 |
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