Stem cells repurpose proliferation to contain a breach in their niche barrier

Adult stem cells are responsible for life-long tissue maintenance. They reside in and interact with specialized tissue microenvironments (niches). Using murine hair follicle as a model, we show that when junctional perturbations in the niche disrupt barrier function, adjacent stem cells dramatically...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Lay, Kenneth, Yuan, Shaopeng, Gur-Cohen, Shiri, Miao, Yuxuan, Han, Tianxiao, Naik, Shruti, Pasolli, H Amalia, Larsen, Samantha B, Fuchs, Elaine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2018
Pynciau:
Stem Cells and Regenerative Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324878/
https://ncbi.nlm.nih.gov/pubmed/30520726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41661
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