SMAD4 Mutation in Small Cell Transformation of Epidermal Growth Factor Receptor Mutated Lung Adenocarcinoma

The large screening of exons 18 to 21 of the epidermal growth factor receptor (EGFR) gene may lead to the discovery of rare, atypical molecular alterations for which the sensitivity to tyrosine kinase inhibitors (TKIs) remains uncertain. We are reporting a rare exon 18 EGFR mutation (p.E709_710 >...

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Detalles Bibliográficos
Publicado en:Oncologist
Main Authors: D'Haene, Nicky, Le Mercier, Marie, Salmon, Isabelle, Mekinda, Zita, Remmelink, Myriam, Berghmans, Thierry
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2018
Assuntos:
Precision Medicine Clinic: Molecular Tumor Board
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324642/
https://ncbi.nlm.nih.gov/pubmed/30413663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0016
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