SMAD4 Mutation in Small Cell Transformation of Epidermal Growth Factor Receptor Mutated Lung Adenocarcinoma

The large screening of exons 18 to 21 of the epidermal growth factor receptor (EGFR) gene may lead to the discovery of rare, atypical molecular alterations for which the sensitivity to tyrosine kinase inhibitors (TKIs) remains uncertain. We are reporting a rare exon 18 EGFR mutation (p.E709_710 >...

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Pubblicato in:Oncologist
Autori principali: D'Haene, Nicky, Le Mercier, Marie, Salmon, Isabelle, Mekinda, Zita, Remmelink, Myriam, Berghmans, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2018
Soggetti:
Precision Medicine Clinic: Molecular Tumor Board
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324642/
https://ncbi.nlm.nih.gov/pubmed/30413663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0016
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