SMAD4 Mutation in Small Cell Transformation of Epidermal Growth Factor Receptor Mutated Lung Adenocarcinoma

The large screening of exons 18 to 21 of the epidermal growth factor receptor (EGFR) gene may lead to the discovery of rare, atypical molecular alterations for which the sensitivity to tyrosine kinase inhibitors (TKIs) remains uncertain. We are reporting a rare exon 18 EGFR mutation (p.E709_710 >...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: D'Haene, Nicky, Le Mercier, Marie, Salmon, Isabelle, Mekinda, Zita, Remmelink, Myriam, Berghmans, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Precision Medicine Clinic: Molecular Tumor Board
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324642/
https://ncbi.nlm.nih.gov/pubmed/30413663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0016
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