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Evaluation of TAK-264, an Antibody-Drug Conjugate in Pancreatic Cancer Cell Lines and Patient-Derived Xenograft Models

BACKGROUND: Antibody-drug conjugates (ADCs) are an emerging technology consisting of an antibody, linker, and toxic agent, which have the potential to offer a targeted therapeutic approach. A novel target recently explored for the treatment of pancreatic cancer is guanylyl cyclase C (GCC). The objec...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Drugs
Asıl Yazarlar: Schreiber, Anna R., Nguyen, Anna, Bagby, Stacey M., Arcaroli, John J., Yacob, Betelehem W., Quackenbush, Kevin, Guy, Joe L., Crowell, Thomas, Stringer, Bradley, Danaee, Hadi, Kalebic, Thea, Messersmith, Wells A., Pitts, Todd M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324574/
https://ncbi.nlm.nih.gov/pubmed/30631747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212697X05666180516120907
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