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Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy
Cancer patients treated with anti-EGFR drugs often develop a dose-limiting pruritic rash of unknown etiology. The aims of our study were to define causal associations from a clinical study of cutaneous and systemic changes in patients treated with gefitinib and use these to develop and characterize...
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| Udgivet i: | Sci Transl Med |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324537/ https://ncbi.nlm.nih.gov/pubmed/23966299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005773 |
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