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Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas

Targeting mutations and amplifications in the EGFR has been successful precision therapy for cancers of the lung, oral cavity and gastrointestinal track. However, a systemic immune reaction manifested by dose-limiting inflammation in the skin and gut has been a consistent adverse effect. To address...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Mascia, Francesca, Schloemann, Derek T., Cataisson, Christophe, McKinnon, Katherine M., Krymskaya, Ludmila, Wolcott, Karen M., Yuspa, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028304/
https://ncbi.nlm.nih.gov/pubmed/27509256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30376
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