Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

Aberrant activation of epithelial-mesenchymal transition (EMT) in carcinoma cells contributes to increased migration and invasion, metastasis, drug resistance, and tumor-initiating capacity. EMT is not always a binary process; rather, cells may exhibit a hybrid epithelial/mesenchymal (E/M) phenotype...

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Udgivet i:APL Bioeng
Main Authors: Jolly, Mohit Kumar, Preca, Bogdan-Tiberius, Tripathi, Satyendra C., Jia, Dongya, George, Jason T., Hanash, Samir M., Brabletz, Thomas, Stemmler, Marc P., Maurer, Jochen, Levine, Herbert
Format: Artigo
Sprog:Inglês
Udgivet: AIP Publishing LLC 2018
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Special Topic: Bioengineering of Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324214/
https://ncbi.nlm.nih.gov/pubmed/31069317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5024874
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