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Roles of the nucleotide exchange factor and chaperone Hsp110 in cellular proteostasis and diseases of protein misfolding

Cellular protein homeostasis (proteostasis) is maintained by a broad network of proteins involved in synthesis, folding, triage, repair and degradation. Chief among these are molecular chaperones and their cofactors that act as powerful protein remodelers. The growing realization that many human pat...

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Détails bibliographiques
Publié dans:Biol Chem
Auteurs principaux: Yakubu, Unekwu M., Morano, Kevin A.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323643/
https://ncbi.nlm.nih.gov/pubmed/29908125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2018-0209
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