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Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s
Hsp70 molecular chaperones function in protein folding in a manner dependent on regulation by co-chaperones. Hsp40s increase the low intrinsic ATPase activity of Hsp70, and nucleotide exchange factors (NEFs) remove ADP after ATP hydrolysis, enabling a new Hsp70 interaction cycle with non-native prot...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478182/ https://ncbi.nlm.nih.gov/pubmed/16688212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601138 |
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