Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging. There is debate concerning the survival percentile that best isolates the genetic component in longevity. Here, we use three-generati...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: van den Berg, Niels, Rodríguez-Girondo, Mar, van Dijk, Ingrid K., Mourits, Rick J., Mandemakers, Kees, Janssens, Angelique A. P. O., Beekman, Marian, Smith, Ken R., Slagboom, P. Eline
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323124/
https://ncbi.nlm.nih.gov/pubmed/30617297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07925-0
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