Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging. There is debate concerning the survival percentile that best isolates the genetic component in longevity. Here, we use three-generati...

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Publicado no:Nat Commun
Main Authors: van den Berg, Niels, Rodríguez-Girondo, Mar, van Dijk, Ingrid K., Mourits, Rick J., Mandemakers, Kees, Janssens, Angelique A. P. O., Beekman, Marian, Smith, Ken R., Slagboom, P. Eline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323124/
https://ncbi.nlm.nih.gov/pubmed/30617297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07925-0
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