Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

Human lifespan variation is mainly determined by environmental factors, whereas the genetic contribution is 25–30% and expected to be polygenic. Two complementary fields go hand in hand in order to unravel the mechanisms of biological aging: genomic and biomarker research. Explorative and candidate...

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Bibliographic Details
Main Authors: Deelen, Joris, Beekman, Marian, Capri, Miriam, Franceschi, Claudio, Slagboom, P Eline
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2013
Subjects:
Prospects & Overviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633240/
https://ncbi.nlm.nih.gov/pubmed/23423909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200148
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