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TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia

Platelets play a critical role in the pathophysiology of peripheral arterial disease (PAD). The mechanisms by which muscle ischemia regulates aggregation of platelets are poorly understood. We have recently identified the Nod-like receptor nucleotide-binding domain leucine rich repeat containing pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Biophys Res Commun
Egile Nagusiak: Vogel, Sebastian, Murthy, Pranav, Cui, Xiangdong, Lotze, Michael T., Zeh, Herbert J., Sachdev, Ulka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322920/
https://ncbi.nlm.nih.gov/pubmed/30522866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.11.125
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