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HMGB1 and TLR4 mediate skeletal muscle recovery in a murine model of hindlimb ischemia

INTRODUCTION: We have previously shown that the danger signal High Mobility Group Box 1 (HMGB1) promotes angiogenesis when administered to ischemic muscle. HMGB1 signals through Toll-like receptor 4 (TLR4) as well as the receptor for advanced glycation end-products (RAGE). However, the actions of th...

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Dettagli Bibliografici
Autori principali: Sachdev, Ulka, Cui, Xiandong, Tzeng, Edith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657591/
https://ncbi.nlm.nih.gov/pubmed/23414695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2012.11.071
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