Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms

Serine peptidases of the prolyl oligopeptidase (POP) family are of substantial therapeutic importance because of their involvement in diseases such as diabetes, cancer, neurological diseases, and autoimmune disorders. Proper annotation and knowledge of substrate specificity mechanisms in this family...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Yadav, Pooja, Goyal, Venuka Durani, Gaur, Neeraj Kailash, Kumar, Ashwani, Gokhale, Sadashiv M., Jamdar, Sahayog N., Makde, Ravindra D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322877/
https://ncbi.nlm.nih.gov/pubmed/30409909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004254
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