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Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans

Acylpeptide hydrolase (APH; EC 3.4.19.1), which belongs to the S9 family of serine peptidases (MEROPS), catalyzes the removal of an N-acylated amino acid from a blocked peptide. The role of this enzyme in mammalian cells has been suggested to be in the clearance of oxidatively damaged proteins as we...

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Autors principals: Are, Venkata Narayana, Ghosh, Biplab, Kumar, Ashwani, Yadav, Pooja, Bhatnagar, Deepak, Jamdar, Sahayog N., Makde, Ravindra D.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157439/
https://ncbi.nlm.nih.gov/pubmed/25195912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14017944
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