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N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2
Perilipin 2 (PLIN2) is a major lipid droplet (LD)-associated protein that regulates intracellular lipid homeostasis and LD formation. Under lipid-deprived conditions, the LD-unbound (free) form of PLIN2 is eliminated in the cytosol by an as yet unknown ubiquitin (Ub)-proteasome pathway that is assoc...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322874/ https://ncbi.nlm.nih.gov/pubmed/30425097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005556 |
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